R2's Genetic Journey - from National Geographics Genographic Project

Your Y-chromosome results identify you as a member of haplogroup R2.

The genetic markers that define your ancestral history reach back roughly 60,000 years to the first common marker of all non-African men, M168, and follow your lineage to present day, ending with M124, the defining marker of haplogroup R2.

If you look at the map highlighting your ancestors' route, you will see that members of haplogroup R2 carry the following Y-chromosome markers:

M168 > M89 > M9 > M45 > M207 > M124

What's a haplogroup, and why do geneticists concentrate on the Y chromosome in their search for markers? For that matter, what's a marker?

Each of us carries DNA that is a combination of genes passed from both our mother and father, giving us traits that range from eye color and height to athleticism and disease susceptibility. One exception is the Y chromosome, which is passed directly from father to son, unchanged, from generation to generation.

Unchanged, that is unless a mutation - a random, naturally occurring, usually harmless change occurs. The mutation, known as a marker, acts as a beacon; it can be mapped through generations because it will be passed down from the man in whom it occurred to his sons, their sons, and every male in his family for thousands of years.

In some instances there may be more than one mutational event that defines a particular branch on the tree. This means that any of these markers can be used to determine your particular haplogroup, since every individual who has one of these markers also has the others.

When geneticists identify such a marker, they try to figure out when it first occurred, and in which geographic region of the world. Each marker is essentially the beginning of a new lineage on the family tree of the human race. Tracking the lineages provides a picture of how small tribes of modern humans in Africa tens of thousands of years ago diversified and spread to populate the world.

A haplogroup is defined by a series of markers that are shared by other men who carry the same random mutations. The markers trace the path your ancestors took as they moved out of Africa. It's difficult to know how many men worldwide belong to any particular haplogroup, or even how many haplogroups there are, because scientists simply don't have enough data yet.

One of the goals of the five-year Genographic Project is to build a large enough database of anthropological genetic data to answer some of these questions. To achieve this, project team members are traveling to all corners of the world to collect more than 100,000 DNA samples from indigenous populations. In addition, we encourage you to contribute your anonymous results to the project database, helping our geneticists reveal more of the answers to our ancient past.

Keep checking these pages; as more information is received, more may be learned about your own genetic history.

Your Ancestral Journey: What We Know Now

M168: Your Earliest Ancestor

 Fast Facts

Time of Emergence: Roughly 50,000 years ago

Place of Origin: Africa

Climate: Temporary retreat of Ice Age; Africa moves from drought to warmer temperatures and moister conditions

Estimated Number of Homo sapiens: Approximately 10,000

Tools and Skills: Stone tools; earliest evidence of art and advanced conceptual skills

Skeletal and archaeological evidence suggest that anatomically modern humans evolved in Africa around 200,000 years ago, and began moving out of Africa to colonize the rest of the world around 60,000 years ago.

The man who gave rise to the first genetic marker in your lineage probably lived in northeast Africa in the region of the Rift Valley, perhaps in present-day Ethiopia , Kenya, or Tanzania, some 31,000 to 79,000 years ago. Scientists put the most likely date for when he lived at around 50,000 years ago. His descendants became the only lineage to survive outside of Africa, making him the common ancestor of every non-African man living today.

But why would man have first ventured out of the familiar African hunting grounds and into unexplored lands? It is likely that a fluctuation in climate may have provided the impetus for your ancestors' exodus out of Africa.

The African ice age was characterized by drought rather than by cold. It was around 50,000 years ago that the ice sheets of northern Europe began to melt, introducing a period of warmer temperatures and moister climate in Africa. Parts of the inhospitable Sahara briefly became habitable. As the drought-ridden desert changed to a savanna, the animals hunted by your ancestors expanded their range and began moving through the newly emerging green corridor of grasslands. Your nomadic ancestors followed the good weather and the animals they hunted, although the exact route they followed remains to be determined.

In addition to a favorable change in climate, around this same time there was a great leap forward in modern humans' intellectual capacity. Many scientists believe that the emergence of language gave us a huge advantage over other early human species. Improved tools and weapons, the ability to plan ahead and cooperate with one another, and an increased capacity to exploit resources in ways we hadn't been able to earlier, all allowed modern humans to rapidly migrate to new territories, exploit new resources, and replace other hominids.

M89: Moving Through the Middle East

Fast Facts

Time of Emergence: 45,000 years ago

Place: Northern Africa or the Middle East

Climate: Middle East: Semiarid grass plains

Estimated Number of Homo sapiens: Tens of thousands

Tools and Skills: Stone, ivory, wood tools

The next male ancestor in your ancestral lineage is the man who gave rise to M89, a marker found in 90 to 95 percent of all non-Africans. This man was born around 45,000 years ago in northern Africa or the Middle East.

The first people to leave Africa likely followed a coastal route that eventually ended in Australia. Your ancestors followed the expanding grasslands and plentiful game to the Middle East and beyond, and were part of the second great wave of migration out of Africa.

Beginning about 40,000 years ago, the climate shifted once again and became colder and more arid. Drought hit Africa and the grasslands reverted to desert, and for the next 20,000 years, the Saharan Gateway was effectively closed. With the desert impassable, your ancestors had two options: remain in the Middle East, or move on. Retreat back to the home continent was not an option.

While many of the descendants of M89 remained in the Middle East, others continued to follow the great herds of buffalo, antelope, woolly mammoths, and other game through what is now modern-day Iran to the vast steppes of Central Asia.

These semiarid grass-covered plains formed an ancient "superhighway" stretching from eastern France to Korea. Your ancestors, having migrated north out of Africa into the Middle East, then traveled both east and west along this Central Asian superhighway. A smaller group continued moving north from the Middle East to Anatolia and the Balkans, trading familiar grasslands for forests and high country.

M9: The Eurasian Clan Spreads Wide and Far

Fast Facts

Time of Emergence: 40,000 years ago

Place: Iran or southern Central Asia

Estimated Number of Homo sapiens: Tens of thousands

Tools and Skills: Upper Paleolithic

Your next ancestor, a man born around 40,000 years ago in Iran or southern Central Asia, gave rise to a genetic marker known as M9, which marked a new lineage diverging from the M89 Middle Eastern Clan. His descendants, of which you are one, spent the next 30,000 years populating much of the planet.

This large lineage, known as the Eurasian Clan, dispersed gradually over thousands of years. Seasoned hunters followed the herds ever eastward, along the vast super highway of Eurasian steppe. Eventually their path was blocked by the massive mountain ranges of south Central Asia - the Hindu Kush, the Tian Shan, and the Himalayas.

The three mountain ranges meet in a region known as the "Pamir Knot," located in present-day Tajikistan. Here the tribes of hunters split into two groups. Some moved north into Central Asia, others moved south into what is now Pakistan and the Indian subcontinent.

These different migration routes through the Pamir Knot region gave rise to separate lineages.
Most people native to the Northern Hemisphere trace their roots to the Eurasian Clan. Nearly all North Americans and East Asians are descended from the man described above, as are most Europeans and many Indians.

M45: The Journey Through Central Asia

Fast Facts

Time of Emergence: 35,000

Place of Origin: Central Asia

Climate: Glaciers expanding over much of Europe

Estimated Number of Homo sapiens: Approximately 100,000

Tools and Skills: Upper Paleolithic (link)

The next marker of your genetic heritage, M45, arose around 35,000 years ago, in a man born in Central Asia. He was part of the M9 Eurasian Clan that had moved to the north of the mountainous Hindu Kush and onto the game-rich steppes of present-day Kazakhstan, Uzbekistan, and southern Siberia.

Although big game was plentiful, the environment on the Eurasian steppes became increasing hostile as the glaciers of the Ice Age began to expand once again. The reduction in rainfall may have induced desertlike conditions on the southern steppes, forcing your ancestors to follow the herds of game north.

To exist in such harsh conditions, they learned to build portable animal-skin shelters and to create weaponry and hunting techniques that would prove successful against the much larger animals they encountered in the colder climates. They compensated for the lack of stone they traditionally used to make weapons by developing smaller points and blades- microliths that could be mounted to bone or wood handles and used effectively. Their tool kit also included bone needles for sewing animal-skin clothing that would both keep them warm and allow them the range of movement needed to hunt the reindeer and mammoth that kept them fed.

Your ancestors' resourcefulness and ability to adapt was critical to survival during the last ice age in Siberia, a region where no other hominid species is known to have lived.

The M45 Central Asian Clan gave rise to many more; the man who was its source is the common ancestor of most Europeans and nearly all Native American men.

M207: Leaving Central Asia

Fast Facts

Time of Emergence: 30,000

Place of Origin: Central Asia

Climate: Glaciers expanding over much of Europe and western Eurasia

Estimated Number of Homo sapiens: Approximately 100,000

Tools and Skills: Upper Paleolithic

After spending considerable time in Central Asia, refining skills to survive in harsh new conditions and exploit new resources, a group from the Central Asian Clan began to head west towards the European subcontinent.

An individual in this clan carried the new M207 mutation on his Y chromosome. His descendants ultimately split into two distinct groups, with one continuing onto the European subcontinent, making this man the ancestor of most Western European men alive today.

But your genetic lineage does not descend from this westward migrating band of hunter-gatherers. The second group did not head west into Europe, but rather likely turned south, ultimately ending their journey in the Indian subcontinent and giving rise to many men whose lineages survive there today. This distribution adds weight to linguistic and archaeological evidence suggesting that a large migration from the Asian steppes into India occurred within the last 10,000 years.

M124: Southward to the Indus Valley

Fast Facts

Time of Emergence: 25,000

Place of Origin: Southern Central Asia

Climate: Ice Age

Estimated Number of Homo sapiens: Hundreds of Thousands

Tools and Skills: Middle Upper Paleolithic

About 25,000 years ago one of your ancestors, who lived in southern Central Asia, first displayed the genetic marker M124. Today M124 defines your haplogroup R2.

The descendants of the first man to carry M124 migrated southward in a forked pattern. They inhabited what is now Pakistan and also, further east, modern India. Today members of haplogroup R2 are found in Northern India, Pakistan and southern Central Asia at frequencies of five to ten percent. Individuals belonging to your R2 lineage made their way as part of the second major wave of human migration into India long after a large wave of African migrants traveled along the Indian coastline some 50,000 to 60,000 years ago.

In addition, members of this distinctive lineage are also found in Eastern Europe among the Gypsy populations of that region. The story told in their genes ties these wandering peoples back to their ancient origins on the Indian subcontinent.

However, the ancient Indian migrations and the distribution of genetic lineages that they ultimately gave rise to remain mysterious. This is because we have precious little data with which to uncover the history of this haplogroup.